ISSN 2149-0287
Clinical Features of Patients with Primary and Secondary Infertility [Bosphorus Med J]
Bosphorus Med J. 2014; 1(1): 5-9

Clinical Features of Patients with Primary and Secondary Infertility

Servet Gencdal1, Deniz Satar2, Emre Destegul1, Orcun Ozdemir1, Adem Altunkol3, Nevzat Can Sener3
1Ministry of Health, Kozan State Hospital, Department of Gynecology and Obstetrics, Adana, Turkey
2Ministry of Health, Numune Tra. and Resa. Hosp. Dept. of Histology and Embryology Adana, Turkey
3Ministry of Health, Numune Training and Research Hospital, Department of Urology, Adana, Turkey

INTRODUCTION: To investigate, in detail, the spermiogram results of cases with primary and secondary infertility and to evaluate the obtained results in light of the data from the literature.
METHODS: A total of 942 cases that had spermiograms performed for primary and secondary infertility at our hospital’s andrology laboratory between November 2008 and December 2010 were included in the study. After the semen was liquefied, macroscopic and microscopic evaluations were performed. Microscopic evaluations involved the assessment of sperm concentration and motility and the evaluation of morphology according to the Kruger strict criteria, all of which were performed in accordance with the criteria of the World Health Organization (WHO). The motility of each sperm was scored according to four categories, which were: rapid forward motility (a), slow forward motility (b), non-progressive motility (c), and immotile (d). Comparison of the spermiogram results of cases with primary and secondary infertility was performed retrospectively according to age (years), volume (ml), sperm concentration (ml/106), total motility (A+B+C) (%), motility A (%), motility B (%), motility C (%), motility D (%), the Total Progressive Motile Sperm Count (TPMSC) and normal morphology (% normal) values. The characteristics of primary and secondary infertility in cases diagnosed with varicocele were also compared. All results were compared statistically.
RESULTS: During the comparisons performed on patients with varicocele according to the type of infertility, no statistical differences were identified with regards to the evaluated parameters. Based on the comparisons performed according to the type of infertility, cases with secondary infertility had higher age, sperm concentration (ml/106), total motility (A+B+C) (%), motility A (%), motility B (%), TPMSC, and normal morphology (% normal) values compared to cases with primary infertility, while motility C (%) and motility D (%) values were higher in cases with primary infertility.
DISCUSSION AND CONCLUSION: As expected, varicocele did not alter sperm parameters when infertility was present. Spermiogram results demonstrated various differences depending on the presence of varicocele, infertility type and many other factors.

Keywords: Varicocele, infertility, sperm concentration, morphology.

Pirimer ve Sekonder İnfertil Hastaların Klinik Özellikleri

Servet Gencdal1, Deniz Satar2, Emre Destegul1, Orcun Ozdemir1, Adem Altunkol3, Nevzat Can Sener3
1Ministry of Health, Kozan State Hospital, Department of Gynecology and Obstetrics, Adana, Turkey
2Ministry of Health, Numune Tra. and Resa. Hosp. Dept. of Histology and Embryology Adana, Turkey
3Ministry of Health, Numune Training and Research Hospital, Department of Urology, Adana, Turkey

GİRİŞ ve AMAÇ: Primer ve sekonder infertil olguların spermiyogram sonuçlarının ayrıntılı bir şekilde incelenmesi ve çıkan sonuçların literatür verileri eşliğinde değerlendirilmesi amaçlanmıştır.
YÖNTEM ve GEREÇLER: Çalışmaya Kasım 2008 ile Aralık 2010 tarihleri arasında hastanemiz androloji laboratuvarında primer ve sekonder infertilite sebebi ile spermiyogram yapılan 942 olgu dahil edildi. Semen likefiye olduktan sonra makroskobik değerlendirme yapıldı ve Dünya Sağlık Örgütü (WHO) kriterlerine göre volüm, sayı, motilite ve Kruger Strict kriterlerine göre morfoloji değerlendirilmesi yapıldı. Her bir spermin motilitesi; hızlı ileri hareketli (a), yavaş ileri hareketli (b), yerinde hareketli (c) ve hareketsiz (d=immotil) olmak üzere 4 kategoride skorlandı.
BULGULAR: Varikosel tanısı olan ve olmayan hastaların karşılaştırılmasında yaş, morfoloji (% normal), sperm konsantrasyonu, motilite total (A+B+C) (%), motilite A (%), motilite B (%), Total Progresif Motil Sperm Sayısı (TPMSS), baş (%) ve boyun (%) değerleri varikosel tanısı olmayan olgularda daha yüksek olarak bulunurken sadece motilite D değeri varikoselli olgularda daha yüksek olarak saptandı. Varikoselli hastalarda infertilite tipine göre yapılan karşılaştırma sonucunda yukarıda verilen parametreler açısından istatiksel farklılık saptanmadı. İnfertilite tipine göre yaptığımız karşılaştırma sonucunda sekonder infertilite özelliklerine sahip olguların yaş, morfoloji (% normal), sperm konsantrasyonu (ml/106 ), TPMSS, motilite total (A+B+C) (%), motilite A (%), motilite B (%) değerleri primer infertilli olgulara göre daha yüksek olarak saptanırken motilite C ve motilite D değerleri ise primer infertiliteli olgularda daha yüksek değerlerde saptanmıştır.
TARTIŞMA ve SONUÇ: Varikoselli olup olmamanın infertilite olması durumunda sperm parametrelerini etkilemediği gözlenmektedir. Spermogram sonuçları infertilite tipine, varikoselli olma durumuna göre ve diğer birçok etkene bağlı olarak değişiklikler göstermektedir.

Anahtar Kelimeler: Varikosel, infertilite, sperm konsantrasyonu, motilite, morfoloji

Servet Gencdal, Deniz Satar, Emre Destegul, Orcun Ozdemir, Adem Altunkol, Nevzat Can Sener. Clinical Features of Patients with Primary and Secondary Infertility. Bosphorus Med J. 2014; 1(1): 5-9

Corresponding Author: Servet Gencdal, Türkiye
Manuscript Language: English
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